Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.43 |
| ▸ | PDE4A | P27815 | 5/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165448 | 0.89 | ALDH1A1 (0.57) | NPSR1ALDH1A1LMNAKDM4EPDE4D | |
| SCHEMBL9170308 | 0.89 | DGAT2 (0.43) | NPSR1ALDH1A1LMNAKDM4EPDE4D | |
| SCHEMBL9169955 | 0.88 | NPSR1 (0.65) | NPSR1ALDH1A1LMNAKDM4EPDE4D | |
| SCHEMBL9167158 | 0.87 | PDE4D (0.48) | NPSR1ALDH1A1LMNAKDM4EPDE4D | |
| SCHEMBL9168944 | 0.86 | ALDH1A1 (0.45) | NPSR1ALDH1A1LMNAKDM4ETRPV1 | |
| SCHEMBL9563052 | 0.82 | NPSR1 (0.50) | NPSR1ALDH1A1LMNAKDM4EPDE4D | |
| SCHEMBL9171431 | 0.82 | NPSR1 (0.50) | NPSR1ALDH1A1LMNAKDM4EPDE4D | |
| SCHEMBL9165629 | 0.82 | NPSR1 (0.62) | NPSR1ALDH1A1LMNAKDM4EPDE4D | |
| SCHEMBL9171807 | 0.81 | NPSR1 (0.75) | NPSR1ALDH1A1LMNAKDM4EPDE4D | |
| SCHEMBL9172634 | 0.81 | NPSR1 (0.61) | NPSR1ALDH1A1LMNAKDM4EPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | claimed |
| US-5405826-A | Herbicidal pyridopyridazinones and pyridopyridazinethiones | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-04-11 | — | — | US | disclosed |
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | disclosed |