Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.53 |
| ▸ | ESR1 | P03372 | 9/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | YES1 | P07947 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.32 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.32 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165781 | 0.71 | ESR1 (0.51) | ESR2ESR1MAOAMAOBMEN1 | |
| SCHEMBL3164641 | 0.71 | ESR1 (0.52) | ESR2ESR1MEN1USP2POLB | |
| SCHEMBL31163959 | 0.63 | — | — | |
| SCHEMBL562630 | 0.63 | ALDH1A1 (0.33) | ESR2ESR1 | |
| SCHEMBL22972963 | 0.63 | — | — | |
| SCHEMBL23767778 | 0.63 | — | — | |
| SCHEMBL4565328 | 0.62 | ESR1 (0.55) | ESR2ESR1BRD4CREBBPCYP19A1 | |
| SCHEMBL9559208 | 0.62 | BRD4 (0.61) | ESR2ESR1BRD4CREBBPMEN1 | |
| SCHEMBL9166727 | 0.62 | ESR1 (0.38) | ESR2ESR1 | |
| SCHEMBL23767850 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9274101-B2 | Methods and kits for obtaining a metabolic profile of living animal cells | BIOLOG, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| EP-1501938-B1 | ANALYSIS OF SUBSTRATE UTILIZATION BY ANIMAL OR PLANT CELLS | BIOLOG INC (US) | 2009-10-21 | — | — | EP | disclosed |
| EP-0402699-B1 | Chromogenic dibenzoxazepinone and dibenzothiazepinone enzyme substrates | MILES INC (US) | 1995-02-22 | — | — | EP | disclosed |
| US-5104980-A | CHROMOGENIC DIBENZOXAZEPINONE AND DIBENZOTHIAZEPINONE ENZYME SUBSTRATES | MILES INC. (US) | 1992-04-14 | — | — | US | disclosed |
| EP-0402699-A2 | Chromogenic dibenzoxazepinone and dibenzothiazepinone enzyme substrates | MILES INC. (US) | 1990-12-19 | — | — | EP | disclosed |