Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 18/20 | 0.51 |
| ▸ | PTPRF | P10586 | 1/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646411 | 0.78 | NQO1 (0.42) | PTPN1MTNR1AMTNR1BMAPTPKM | |
| SCHEMBL10759307 | 0.76 | PTPN1 (0.48) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL5743653 | 0.72 | PTPN1 (0.83) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL8802432 | 0.71 | KMT2A (0.39) | MTNR1AMTNR1BMAPT | |
| SCHEMBL9176591 | 0.70 | CALM1 (0.31) | — | |
| SCHEMBL9172238 | 0.70 | PTPN1 (0.46) | PTPN1 | |
| SCHEMBL3865070 | 0.70 | ALDH1A1 (0.42) | PTPN1MAPTPKM | |
| SCHEMBL3868415 | 0.69 | PTPN1 (0.97) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL6955273 | 0.68 | CALM1 (0.43) | — | |
| SCHEMBL12892177 | 0.68 | ACP1 (0.53) | PTPN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640080-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS. | SYNTEX INC (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5380739-A | Angiotensin II antagonists | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993023391-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-11-25 | — | — | WO | disclosed |