Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | VKORC1 | Q9BQB6 | 2/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9172007 | 0.78 | PTPN1 (0.51) | PTPN1MAPTPKMMTNR1AMTNR1B | |
| SCHEMBL12892177 | 0.78 | ACP1 (0.53) | PTPN1PKMCA12CA9MEN1 | |
| SCHEMBL10372971 | 0.76 | KDM4E (0.41) | NQO1MAPTPKMCA12CA9 | |
| SCHEMBL26128173 | 0.74 | KDM4E (0.40) | MAPTPKMCA12CA9MEN1 | |
| SCHEMBL8711671 | 0.71 | DDR2 (0.56) | NQO1MAPTPKMCA12CA9 | |
| SCHEMBL7647208 | 0.70 | BCL2 (0.32) | MEN1KMT2AHSD17B10 | |
| SCHEMBL31652584 | 0.70 | RAB9A (0.42) | PKMCA12CA9MEN1KMT2A | |
| SCHEMBL7671396 | 0.70 | CYP2D6 (0.34) | PTPN1MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6955273 | 0.68 | CALM1 (0.43) | CA12CA9POLB | |
| SCHEMBL10370972 | 0.68 | TSHR (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3332234-B2 | — | — | 2002-10-07 | — | — | JP | claimed |
| EP-0640080-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS. | SYNTEX INC (US) | 1995-03-01 | — | — | EP | claimed |
| WO-1993023391-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-11-25 | — | — | WO | claimed |