Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | HTR2B | P41595 | 2/20 | 0.58 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11035003 | 0.99 | LMNA (0.57) | LMNAHTR2AHTR2CHTR2BHTR4 | |
| SCHEMBL5473818 | 0.80 | HTR4 (0.70) | LMNAHTR4GAAMEN1KMT2A | |
| SCHEMBL12123626 | 0.78 | LMNA (0.64) | LMNAHTR4GAAALDH1A1MEN1 | |
| SCHEMBL14946906 | 0.78 | LMNA (0.61) | LMNAHTR2AHTR2CHTR2BGAA | |
| SCHEMBL12123622 | 0.77 | ALDH1A1 (0.67) | LMNAHTR2AALDH1A1MEN1KMT2A | |
| SCHEMBL18215257 | 0.77 | KMT2A (0.63) | LMNAGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL29944079 | 0.77 | KMT2A (0.63) | LMNAGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL5056515 | 0.76 | LMNA (0.56) | LMNAHTR2AHTR2CHTR2BALDH1A1 | |
| SCHEMBL22778843 | 0.76 | LMNA (0.82) | LMNAGAAALDH1A1KDM4EMEN1 | |
| SCHEMBL8574065 | 0.76 | HTR2C (0.69) | HTR2AHTR2CHTR2BHTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273375-B2 | Propiophenone derivatives for treatment of pollakiuria (frequency urination) | HOKURIKU PHARMACEUTICAL (JP) | 1995-05-10 | — | — | EP | disclosed |
| US-4912116-A | Propiophenone derivatives for treatment of pollakiuria (frequency urination) | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1990-03-27 | — | — | US | disclosed |