Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.75 |
| ▸ | GNG2 | P59768 | 5/20 | 0.72 |
| ▸ | GNB1 | P62873 | 5/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | P2RY2 | P41231 | 7/20 | 0.61 |
| ▸ | P2RY4 | P51582 | 9/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.57 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.57 |
| ▸ | ENTPD1 | P49961 | 2/20 | 0.57 |
| ▸ | MET | P08581 | 2/20 | 0.56 |
| ▸ | HGF | P14210 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18089411 | 0.91 | PHLPP2 (0.65) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL13021512 | 0.88 | GNG2 (0.92) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL9173299 | 0.86 | PHLPP2 (1.00) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL29666889 | 0.86 | PHLPP2 (1.00) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL2854079 | 0.85 | PHLPP2 (0.98) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL2779595 | 0.84 | GNG2 (1.00) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL9137161 | 0.84 | GNG2 (0.82) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL10866254 | 0.84 | GNG2 (0.71) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL13213975 | 0.84 | GNG2 (0.86) | PHLPP2GNG2GNB1CYP1A2CYP2C9 | |
| SCHEMBL2778161 | 0.84 | GNG2 (1.00) | PHLPP2GNG2GNB1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385842-A | Anthraquinones as inhibitors of sulfide production from sulfate-reducing bacteria | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-31 | — | — | US | disclosed |
| WO-1991015954-A1 | ANTHRAQUINONES AS INHIBITORS OF SULFIDE PRODUCTION FROM SULFATE-REDUCING BACTERIA | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-31 | — | — | WO | disclosed |
| US-4773914-A | Process for trichromatic dyeing polyamide fibres | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-27 | — | — | US | disclosed |