Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 4/20 | 0.50 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | AGER | Q15109 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.47 |
| ▸ | KDM5A | P29375 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364528 | 0.83 | HTT (0.56) | DHODHALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL9172338 | 0.82 | DHODH (0.53) | DHODHLTC4SKDM5AKDM4CKDM5B | |
| SCHEMBL9229632 | 0.81 | POLB (0.55) | DHODHALDH1A1LTC4SMRGPRX4KAT6A | |
| SCHEMBL7368545 | 0.81 | ALDH1A1 (0.63) | DHODHALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL7366436 | 0.78 | KDM4E (0.51) | DHODHALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL9229219 | 0.78 | KAT6A (0.48) | DHODHLTC4SKDM5AKDM4CKDM5B | |
| SCHEMBL690501 | 0.78 | KAT6A (0.54) | L3MBTL1MRGPRX4KAT6A | |
| SCHEMBL9226099 | 0.78 | LTC4S (0.56) | DHODHLTC4SKDM5AKDM4CKDM5B | |
| SCHEMBL7372993 | 0.77 | TDP1 (0.52) | DHODHRUNX1ALDH1A1KDM4ENPSR1 | |
| SCHEMBL30668192 | 0.76 | KAT6A (0.57) | ALDH1A1L3MBTL1MRGPRX4KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393730-A | Preemergence, postemergence herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-02-28 | — | — | US | claimed |
| EP-0606843-A1 | Nicotinic acid derivative | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-07-20 | — | — | EP | claimed |
| US-5405826-A | Herbicidal pyridopyridazinones and pyridopyridazinethiones | RHONE POULENC AGRICULTURE LIMITED (GB) | 1995-04-11 | — | — | US | disclosed |
| US-5393730-A | Preemergence, postemergence herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1995-02-28 | — | — | US | disclosed |
| EP-0606843-A1 | Nicotinic acid derivative | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-07-20 | — | — | EP | disclosed |
| EP-0555957-A1 | Pyrido 2,3-d pyridazine derivatives as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1993-08-18 | — | — | EP | disclosed |