Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9176347 | 0.92 | MAPT (0.43) | LMNAMAPTPKMALOX12SMN1; SMN2 | |
| SCHEMBL9176287 | 0.90 | LMNA (0.39) | HTTLMNAMAPTPKMALOX12 | |
| SCHEMBL9174730 | 0.89 | ALDH1A1 (0.43) | HTTLMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9173038 | 0.88 | TP53 (0.39) | HTTLMNAMAPTPKMALOX12 | |
| SCHEMBL9173102 | 0.86 | MAPT (0.40) | HTTLMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9174714 | 0.83 | LMNA (0.42) | HTTLMNAMAPTPKMALOX12 | |
| SCHEMBL8407202 | 0.83 | YAP1 (0.49) | HTTLMNAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL9173930 | 0.82 | ALDH1A1 (0.39) | HTTLMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9176283 | 0.82 | SMN1; SMN2 (0.40) | HTTLMNAMAPTPKMALOX12 | |
| SCHEMBL662822 | 0.80 | LMNA (0.48) | HTTLMNAMAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442064-A | Anticoagulants, antiagglomerants | DR. KARL THOMAE GMBH (DE) | 1995-08-15 | — | — | US | disclosed |
| EP-0592949-A2 | N-(aminocarbonyl)-piperidines/pepirazines as aggregation inhibiting agents | Dr. Karl Thomae GmbH (DE) | 1994-04-20 | — | — | EP | disclosed |