SCHEMBL91748

SCHEMBL91748

Cc1cc(C2CCC(C)CO2)cc(C)c1-c1ccc(C(=O)Oc2cc(F)c(C)c(F)c2)cc1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CLK2 P49760 1/20 0.31
EPHX2 P34913 1/20 0.31
CYP2C9 P11712 1/20 0.30
MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91747 0.91 SLC6A3 (0.34)
SCHEMBL91799 0.90
SCHEMBL91764 0.87
SCHEMBL91816 0.87 KMT2A (0.39) CYP2C9
SCHEMBL91794 0.87 KDM4E (0.31)
SCHEMBL91686 0.84 KMT2A (0.32) CLK2EPHX2
SCHEMBL91788 0.83 KMT2A (0.40) EPHX2
SCHEMBL91809 0.83 KMT2A (0.32)
SCHEMBL91737 0.82 HSD11B1 (0.33)
SCHEMBL13433615 0.81 CLK2 (0.33) CLK2EPHX2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129002-B2 Compounds for use in liquid crystal media MERCK PATENT GMBH (DE) 2012-03-06 US disclosed
US-7419706-B2 Liquid crystalline medium MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-09-02 US disclosed