Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91794 | 0.90 | KDM4E (0.31) | KMT2AMAPTALDH1A1KDM4EGLA | |
| SCHEMBL91747 | 0.87 | SLC6A3 (0.34) | KMT2AGBA1MAPTALDH1A1KDM4E | |
| SCHEMBL91788 | 0.87 | KMT2A (0.40) | KMT2AGBA1MAPTALDH1A1KDM4E | |
| SCHEMBL91816 | 0.83 | KMT2A (0.39) | KMT2AGBA1MAPTALDH1A1GAA | |
| SCHEMBL91905 | 0.83 | ESR1 (0.33) | — | |
| SCHEMBL91748 | 0.83 | CLK2 (0.31) | — | |
| SCHEMBL91793 | 0.82 | — | — | |
| SCHEMBL91799 | 0.81 | — | — | |
| SCHEMBL91790 | 0.80 | — | — | |
| SCHEMBL14075364 | 0.78 | PRKAG1 (0.31) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |