Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.48 |
| ▸ | KCNA5 | P22460 | 5/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | GRM8 | O00222 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831743 | 0.81 | POLB (0.38) | KCNA5KCNN4CYP19A1SMN1; SMN2CTSL | |
| SCHEMBL6344248 | 0.81 | CYP19A1 (0.50) | KCNA5KCNN4CYP19A1SMN1; SMN2LMNA | |
| SCHEMBL4452256 | 0.71 | SMN1; SMN2 (0.50) | KCNA5CYP19A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL4452260 | 0.71 | SMN1; SMN2 (0.50) | KCNA5CYP19A1SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL9173752 | 0.69 | CYP2A6 (0.53) | FDPS | |
| SCHEMBL12303932 | 0.68 | CYP19A1 (0.47) | KCNA5CYP19A1SMN1; SMN2CTSLCTSS | |
| SCHEMBL128718 | 0.68 | CFTR (0.53) | KCNA5KCNN4CYP19A1SMN1; SMN2CFTR | |
| SCHEMBL5666093 | 0.68 | PGK1 (0.57) | FDPSKCNA5KCNN4GRM8GRM4 | |
| SCHEMBL4443428 | 0.67 | FDPS (0.50) | FDPSKCNA5KCNN4GRM8GRM4 | |
| SCHEMBL9218051 | 0.67 | FDPS (0.46) | FDPSKCNA5KCNN4GRM8GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544812-B1 | BISPHOSPHONIC ACID DERIVATIVES AS ANTI-ARTHRITIC AGENTS | UPJOHN CO (US) | 1995-04-05 | — | — | EP | claimed |