SCHEMBL917567

SCHEMBL917567

COCCOCCOCCOCCOCCC(=O)OC(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.37
DGAT1 O75907 1/20 0.33
HDAC3 O15379 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TLR2 O60603 1/20 0.32
TLR1 Q15399 1/20 0.32
CA2 P00918 2/20 0.32
CA12 O43570 1/20 0.32
CA14 Q9ULX7 1/20 0.32
TSHR P16473 1/20 0.31
EPHX2 P34913 1/20 0.31
CYP2D6 P10635 1/20 0.30
MLYCD O95822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29467689 1.00 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2
SCHEMBL19532914 1.00 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2
SCHEMBL29467625 1.00 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2
SCHEMBL12592808 1.00 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2
SCHEMBL1781057 1.00 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2
SCHEMBL916562 1.00 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2
SCHEMBL24668232 1.00 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2
SCHEMBL917272 1.00 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2
SCHEMBL21877221 1.00 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2
SCHEMBL5737163 0.92 STING1 (0.37) STING1DGAT1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2626368-B1 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LTD (IN) 2016-12-21 EP disclosed
EP-2626368-B1 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LTD (IN) 2016-12-21 EP disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9101596-B2 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
US-9102758-B2 Insulin-oligomer conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2015-08-11 US disclosed
EP-1773878-B1 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF BIOCON LTD (IN) 2015-03-04 EP disclosed
EP-1773878-B1 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF BIOCON LTD (IN) 2015-03-04 EP disclosed
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF RADHAKRISHNAN BALASINGAM 2010-04-29 US disclosed
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF RADHAKRISHNAN BALASINGAM 2010-04-29 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
US-7605123-B2 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LTD. (IN) 2009-10-20 US disclosed
EP-1773878-A2 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF Nobex Corporation (US) 2007-04-18 EP disclosed
WO-2006014673-A2 INSULIN-OLIGOMER CONJUGATES, FORMULATIONS AND USES THEREOF NOBEX CORPORATION (US) 2006-02-09 WO disclosed
US-20060018874-A1 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof BIOCON LIMITED (IN) 2006-01-26 US disclosed
US-20060019874-A1 Cation complexes of insulin compund conjugates, formulation and uses thereof NOBEX CORPORATION 2006-01-26 US disclosed
US-20060019873-A1 Cation complexes of insulin compound conjugates, formulations and uses thereof BIOCON LIMITED (IN) 2006-01-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060019873-A1 Cation complexes of insulin compound conjugates, formulations and uses thereof GPR119, INSR, IAPP STING1 4575/4885DGAT1 1210/4885HDAC3 414/4885
US-20100105605-A1 FATTY ACID FORMULATIONS AND ORAL DELIVERY OF PROTEINS AND PEPTIDES, AND USES THEREOF FABP2, SLC27A1, SLC27A2 STING1 2607/4885DGAT1 146/4885HDAC3 1818/4885
US-20060018874-A1 Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof FABP2, SLC27A1, SLC27A2 STING1 2672/4885DGAT1 142/4885HDAC3 1797/4885
US-20060019874-A1 Cation complexes of insulin compund conjugates, formulation and uses thereof INSR, GPR119, IAPP STING1 3621/4885DGAT1 280/4885HDAC3 356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.