Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 15/20 | 0.51 |
| ▸ | NQO2 | P16083 | 8/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333208 | 0.81 | MTNR1A (0.51) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8923231 | 0.79 | POLB (0.51) | MTNR1AMTNR1B | |
| SCHEMBL19838588 | 0.76 | MTNR1A (0.59) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL2819328 | 0.75 | HTR2C (0.48) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8609522 | 0.74 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL10467287 | 0.73 | MTNR1B (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL9630789 | 0.73 | MTNR1A (0.60) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL1842495 | 0.73 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL30746730 | 0.73 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8501324 | 0.72 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014002110-A1 | SUBSTITUTUED PYRAZOLE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF. | RALLIS INDIA LIMITED (IN) | 2014-01-03 | — | — | WO | disclosed |
| EP-0530087-B1 | Naphthylethylurea and naphthylethylthiourea compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-05-03 | — | — | EP | disclosed |
| US-5318994-A | Treating melatoninergic disorders | ADIR ET COMPAGNIE (FR) | 1994-06-07 | — | — | US | disclosed |
| EP-0447285-B1 | NAPHTHALENE DERIVATIVES, PROCEDURE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1993-05-12 | — | — | EP | disclosed |
| EP-0530087-A1 | Naphthylethylurea and naphthylethylthiourea compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-03-03 | — | — | EP | disclosed |
| EP-0447285-A1 | Naphthalene derivatives, procedure for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1991-09-18 | — | — | EP | disclosed |