Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.61 |
| ▸ | NQO2 | P16083 | 7/20 | 0.60 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4427914 | 1.00 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2PDE4APDE4B | |
| SCHEMBL2466357 | 1.00 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2PDE4APDE4B | |
| SCHEMBL11602838 | 0.92 | MEN1 (0.57) | MTNR1AMTNR1BNQO2KDM1AMAOA | |
| SCHEMBL4710772 | 0.89 | CA12 (0.64) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL5457802 | 0.87 | PDE4A (0.55) | MTNR1AMTNR1BNQO2PDE4APDE4B | |
| SCHEMBL9630654 | 0.84 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2PDE4APDE4B | |
| SCHEMBL14374375 | 0.83 | ACHE (0.76) | MAOAMAOBACHE | |
| SCHEMBL7272139 | 0.82 | LMNA (0.58) | MTNR1AMTNR1BNQO2ACHE | |
| SCHEMBL7270912 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7270914 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877218-A | PARKINSON'S DISEASE; ANTIEPILEPSY AGENTS; ANTICONVULSANTS | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1999-03-02 | — | — | US | claimed |