Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175728 | 1.00 | POLB (0.61) | POLBTAAR1GAAALDH1A1KMT2A | |
| SCHEMBL27109144 | 0.73 | KEAP1 (0.57) | POLBALDH1A1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL21952420 | 0.71 | ALDH1A1 (0.47) | POLBALDH1A1TSHRHSD17B10KDM4E | |
| Benzoic Acid SCHEMBL6049039 | 0.71 | TDP1 (0.62) | POLBTAAR1GAAALDH1A1KMT2A | |
| SCHEMBL31737192 | 0.71 | POLB (0.54) | POLBTAAR1GAAALDH1A1KMT2A | |
| SCHEMBL10739512 | 0.71 | POLB (0.54) | POLBTAAR1GAAALDH1A1KMT2A | |
| SCHEMBL174303 | 0.71 | POLB (0.54) | POLBTAAR1GAAALDH1A1KMT2A | |
| SCHEMBL14433706 | 0.71 | POLB (0.54) | POLBTAAR1GAAALDH1A1KMT2A | |
| SCHEMBL10739509 | 0.71 | POLB (0.54) | POLBTAAR1GAAALDH1A1KMT2A | |
| SCHEMBL14036245 | 0.70 | ALDH1A1 (0.56) | POLBALDH1A1SMN1; SMN2TDP1KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411333-B1 | Antiherpes tetrapeptide derivatives having a substituted aspartic acid side chain | BIO MEGA BOEHRINGER INGELHEIM (CA) | 1995-05-31 | — | — | EP | disclosed |