Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 8/20 | 0.37 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.37 |
| ▸ | TUBB | P07437 | 3/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9174233 | 0.88 | MAPT (0.39) | NR4A2IDO1TUBB4ATUBBTUBA3C | |
| SCHEMBL9038781 | 0.84 | F7 (0.47) | F7F3CDK4CCND1NR4A2 | |
| SCHEMBL9180404 | 0.83 | NPC1 (0.46) | F7F3CDK4CCND1IDO1 | |
| SCHEMBL9171444 | 0.77 | IDO1 (0.48) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9177126 | 0.76 | IDO1 (0.48) | NR4A2IDO1TUBB4ATUBBTUBA3C | |
| SCHEMBL9178289 | 0.74 | IDO1 (0.45) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| Hydrochloric Acid SCHEMBL9176166 | 0.73 | OPRM1 (0.46) | IDO1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9178079 | 0.72 | SLC6A4 (0.53) | F7F3IDO1TUBB4ATUBB | |
| SCHEMBL9031186 | 0.72 | GABRA1 (0.48) | NR4A2 | |
| Hydrochloric Acid SCHEMBL9176359 | 0.71 | SLC6A4 (0.52) | F7F3IDO1TUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5418242-A | Piperidinylthioindole derivatives, their methods of preparation and pharmaceutical compositions in which they are present, useful especially as analgesics | LABORATOIRES UPSA (FR) | 1995-05-23 | — | — | US | disclosed |