Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119041 | 0.89 | MMP14 (0.33) | MMP14ALDH1A1LMNA | |
| SCHEMBL10119042 | 0.88 | ALDH1A1 (0.41) | HTTMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL18211000 | 0.86 | MMP14 (0.31) | MMP14 | |
| SCHEMBL18210996 | 0.85 | ALDH1A1 (0.38) | HTTMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL10119044 | 0.85 | MMP14 (0.33) | MAPTL3MBTL1SMN1; SMN2TDP1MAPK1 | |
| SCHEMBL9175096 | 0.82 | HTT (0.45) | HTTTP53MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL18211003 | 0.82 | MMP14 (0.32) | MAPTL3MBTL1MMP14ALDH1A1LMNA | |
| SCHEMBL4777142 | 0.82 | HTT (0.45) | HTTTP53MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL2602717 | 0.81 | MMP14 (0.47) | HTTMAPTL3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL6932967 | 0.81 | MMP14 (0.47) | HTTMAPTL3MBTL1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474402-B1 | Chromophore-containing compounds for opto-electronic applications | ICI PLC (GB) | 1995-05-24 | — | — | EP | disclosed |
| US-5290630-A | Chromophore-containing compounds for opto-electronic applications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-03-01 | — | — | US | disclosed |
| EP-0474402-A2 | Chromophore-containing compounds for opto-electronic applications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-03-11 | — | — | EP | disclosed |