D-Glutamate

D-Glutamate

SCHEMBL9176409

CC(C)CC(N)C(=O)O.NC(CCC(=O)O)C(=O)O.NC(CCC(=O)O)C(=O)O

nearest known ligand 0.72

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 5/20 0.72
SLC1A2 P43004 5/20 0.72
SLC1A1 P43005 4/20 0.72
CYP1A2 P05177 2/20 0.72
GRM8 O00222 2/20 0.72
GRM6 O15303 2/20 0.72
GRM7 Q14831 2/20 0.72
GRM4 Q14833 2/20 0.72
GRIK1 P39086 2/20 0.72
GRIK2 Q13002 2/20 0.72
SLC7A5 Q01650 1/20 0.72
GRIN2D O15399 1/20 0.72
GRIN3B O60391 1/20 0.72
GSR P00390 1/20 0.72
GRM5 P41594 1/20 0.72
GRIA1 P42261 1/20 0.72
GRIA2 P42262 1/20 0.72
GRIA3 P42263 1/20 0.72
GRIA4 P48058 1/20 0.72
GRIN1 Q05586 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL5614072 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL6130437 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL24357 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL1126187 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
D-Glutamate SCHEMBL3512077 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
D-Glutamate SCHEMBL19876607 0.96 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL17926909 0.96 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL1365479 0.96 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL429944 0.94 SLC1A3 (0.64) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
D-Glutamate SCHEMBL21410037 0.94 SLC1A3 (0.64) SLC1A3SLC1A2SLC1A1CYP1A2GRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5462866-A Central portion is solution of polyanion containing biological material, outer membrane enclosing central portion is complex of the polyanion and a polycation VANDERBILT UNIVERSITY (US) 1995-10-31 US disclosed
US-5260002-A Forming spheres from polyanions or polycations with polymerization VANDERBILT UNIVERSITY (US) 1993-11-09 US disclosed
WO-1993012875-A1 METHOD AND APPARATUS FOR PRODUCING UNIFORM POLYMERIC SPHERES VANDERBILT UNIVERSITY (US) 1993-07-08 WO disclosed