Glutamic Acid

Glutamic Acid

SCHEMBL1126187

CC(C)C[C@@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 5/20 0.72
SLC1A2 P43004 5/20 0.72
SLC1A1 P43005 4/20 0.72
CYP1A2 P05177 2/20 0.72
GRM8 O00222 2/20 0.72
GRM6 O15303 2/20 0.72
GRM7 Q14831 2/20 0.72
GRM4 Q14833 2/20 0.72
GRIK1 P39086 2/20 0.72
GRIK2 Q13002 2/20 0.72
SLC7A5 Q01650 1/20 0.72
GRIN2D O15399 1/20 0.72
GRIN3B O60391 1/20 0.72
GSR P00390 1/20 0.72
GRM5 P41594 1/20 0.72
GRIA1 P42261 1/20 0.72
GRIA2 P42262 1/20 0.72
GRIA3 P42263 1/20 0.72
GRIA4 P48058 1/20 0.72
GRIN1 Q05586 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutamic Acid SCHEMBL5614072 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
D-Glutamate SCHEMBL9176409 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL6130437 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL24357 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
D-Glutamate SCHEMBL3512077 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
D-Glutamate SCHEMBL19876607 0.96 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL17926909 0.96 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL1365479 0.96 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL429944 0.94 SLC1A3 (0.64) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
D-Glutamate SCHEMBL21410037 0.94 SLC1A3 (0.64) SLC1A3SLC1A2SLC1A1CYP1A2GRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8258190-B2 Encapsulated contrast agents INTEZYNE TECHNOLOGIES, INC. (US) 2012-09-04 US claimed
EP-2152320-A2 ENCAPSULATED CONTRAST AGENTS Intezyne Technologies Incorporated (US) 2010-02-17 EP claimed
US-20090092554-A1 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2009-04-09 US claimed
WO-2008134734-A2 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2008-11-06 WO claimed
US-8258190-B2 Encapsulated contrast agents INTEZYNE TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2283063-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS Intezyne Technologies Inc. (US) 2011-02-16 EP disclosed
EP-2152320-A2 ENCAPSULATED CONTRAST AGENTS Intezyne Technologies Incorporated (US) 2010-02-17 EP disclosed
US-20090286938-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS INTEZYNE TECHNOLOGIES, INC. (US) 2009-11-19 US disclosed
WO-2009134984-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS INTEZYNE TECHNOLGIES INC. (US) 2009-11-05 WO disclosed
US-20090092554-A1 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2009-04-09 US disclosed
WO-2008134734-A2 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2008-11-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286938-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS PFAS, GFPT1, PFKFB4 SLC1A3 282/4885SLC1A2 803/4885SLC1A1 419/4885
US-20090092554-A1 ENCAPSULATED CONTRAST AGENTS LIPA, LPXN, CD47 SLC1A3 3317/4885SLC1A2 3748/4885SLC1A1 3133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.