Glutamic Acid

Glutamic Acid

SCHEMBL1126187

CC(C)C[C@@H](N)C(=O)O.N[C@@H](CCC(=O)O)C(=O)O

nearest known ligand 0.72

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC1A3 P43003 5/20 0.72
▸ SLC1A2 P43004 5/20 0.72
▸ SLC1A1 P43005 4/20 0.72
▸ CYP1A2 P05177 2/20 0.72
▸ GRM8 O00222 2/20 0.72
▸ GRM6 O15303 2/20 0.72
▸ GRM7 Q14831 2/20 0.72
▸ GRM4 Q14833 2/20 0.72
▸ GRIK1 P39086 2/20 0.72
▸ GRIK2 Q13002 2/20 0.72
▸ SLC7A5 Q01650 1/20 0.72
▸ GRIN2D O15399 1/20 0.72
▸ GRIN3B O60391 1/20 0.72
▸ GSR P00390 1/20 0.72
▸ GRM5 P41594 1/20 0.72
▸ GRIA1 P42261 1/20 0.72
▸ GRIA2 P42262 1/20 0.72
▸ GRIA3 P42263 1/20 0.72
▸ GRIA4 P48058 1/20 0.72
▸ GRIN1 Q05586 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
D-Glutamate SCHEMBL9176409 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
D-Glutamate SCHEMBL3512077 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL5614072 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL6130437 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL24357 1.00 SLC1A3 (0.72) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
D-Glutamate SCHEMBL19876607 0.96 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL17926909 0.96 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL1365479 0.96 SLC1A3 (0.67) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL18249491 0.94 SLC1A3 (0.64) SLC1A3SLC1A2SLC1A1CYP1A2GRM8
Glutamic Acid SCHEMBL429944 0.94 SLC1A3 (0.64) SLC1A3SLC1A2SLC1A1CYP1A2GRM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8258190-B2 Encapsulated contrast agents INTEZYNE TECHNOLOGIES, INC. (US) 2012-09-04 — — US claimed
EP-2152320-A2 ENCAPSULATED CONTRAST AGENTS Intezyne Technologies Incorporated (US) 2010-02-17 — — EP claimed
US-20090092554-A1 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2009-04-09 — — US claimed
WO-2008134734-A2 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2008-11-06 — — WO claimed
US-8258190-B2 Encapsulated contrast agents INTEZYNE TECHNOLOGIES, INC. (US) 2012-09-04 — — US disclosed
EP-2283063-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS Intezyne Technologies Inc. (US) 2011-02-16 — — EP disclosed
EP-2152320-A2 ENCAPSULATED CONTRAST AGENTS Intezyne Technologies Incorporated (US) 2010-02-17 — — EP disclosed
US-20090286938-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS INTEZYNE TECHNOLOGIES, INC. (US) 2009-11-19 — — US disclosed
WO-2009134984-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS INTEZYNE TECHNOLGIES INC. (US) 2009-11-05 — — WO disclosed
US-20090092554-A1 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2009-04-09 — — US disclosed
WO-2008134734-A2 ENCAPSULATED CONTRAST AGENTS INTEZYNE TECHNOLOGIES, INC. (US) 2008-11-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286938-A1 SYNTHESIS OF HYBRID BLOCK COPOLYMERS FROM DIFLUOROACETATE AMMONIUM SALTS PFAS, GFPT1, PFKFB4 SLC1A3 282/4885SLC1A2 803/4885SLC1A1 419/4885
US-20090092554-A1 ENCAPSULATED CONTRAST AGENTS LIPA, LPXN, CD47 SLC1A3 3317/4885SLC1A2 3748/4885SLC1A1 3133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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