Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158352 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTTP53TSHRHPGD | |
| SCHEMBL7010144 | 0.80 | ALOX5AP (0.54) | ALDH1A1MAPTTSHRMEN1KMT2A | |
| SCHEMBL9176534 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MAPTTP53TSHRHPGD | |
| SCHEMBL5599199 | 0.75 | TDP1 (0.41) | ALDH1A1MAPTTP53TSHRHPGD | |
| SCHEMBL14804292 | 0.73 | ALDH1A1 (0.42) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL24556914 | 0.72 | LTA4H (0.38) | PKMGAAOPRM1 | |
| SCHEMBL29411927 | 0.72 | TDP1 (0.68) | ALDH1A1MAPTTP53TSHRHPGD | |
| SCHEMBL159569 | 0.72 | ALOX5AP (0.64) | ALDH1A1MAPTTP53TSHRHPGD | |
| SCHEMBL28633766 | 0.71 | ALDH1A1 (0.44) | ALDH1A1MAPTTP53TSHRHPGD | |
| SCHEMBL21094081 | 0.70 | TDP1 (0.79) | ALDH1A1MAPTTP53TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10870724-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-12-22 | — | — | US | disclosed |
| US-10465037-B2 | High heat monomers and methods of use thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-11-05 | — | — | US | disclosed |
| US-20190322653-A1 | METHODS FOR SYNTHESIZING HIGH PURITY EPOXY COMPOUNDS AND PRODUCTS OBTAINED THEREFROM | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-10-24 | — | — | US | disclosed |
| US-20170158806-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-08 | — | — | US | disclosed |
| US-20170158806-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-08 | — | — | US | disclosed |
| WO-2016014536-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2016-01-28 | — | — | WO | disclosed |
| EP-0325058-B1 | Improved epoxide resin compositions and method | MINNESOTA MINING & MFG (US) | 1995-05-17 | — | — | EP | disclosed |
| US-5073595-A | Fluorene chain extender; improved glass transition temperature toughness | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-5045363-A | Chain extended with a 9,9-bis(hydroxyphenyl)fluorene compound, improved toughness, adhesive bonding film | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-09-03 | — | — | US | disclosed |
| US-4983672-A | Containing 9,9-bis(hydroxyphenyl)fluorene | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-01-08 | — | — | US | disclosed |
| US-4980234-A | CONTAINING SUBSTITUTED FLUORENE UNITS | MINNESOTA MINING AND MANUFACTURING CO. (US) | 1990-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10870724-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB1, EPHX2 | ALDH1A1 318/4885MAPT 969/4885TP53 710/4885 |
| US-20170158806-A1 | HIGH HEAT MONOMERS AND METHODS OF USE THEREOF | HSP90AA1, HSP90AB1, EPHX2 | ALDH1A1 318/4885MAPT 969/4885TP53 710/4885 |
| US-10465037-B2 | High heat monomers and methods of use thereof | HSP90AA1, HSP90AB2P, HSP90AB1 | ALDH1A1 295/4885MAPT 990/4885TP53 794/4885 |
| US-20190322653-A1 | METHODS FOR SYNTHESIZING HIGH PURITY EPOXY COMPOUNDS AND PRODUCTS OBTAINED THEREFROM | EPHX2, EPHX1, CYP2F1 | ALDH1A1 138/4885MAPT 4864/4885TP53 3230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.