SCHEMBL9178152

SCHEMBL9178152

COCOc1ccc(CCCCC(=O)O)cc1OCOC

nearest known ligand 0.51

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.51
SELP P16109 1/20 0.46
ALOX5 P09917 1/20 0.45
MAPT P10636 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
PPARG P37231 1/20 0.44
BIRC5 O15392 1/20 0.43
CYP1A2 P05177 1/20 0.43
FFAR4 Q5NUL3 3/20 0.43
FFAR1 O14842 2/20 0.43
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
APP P05067 1/20 0.43
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9175204 0.94 PPARA (0.58) PPARASELPALOX5PPARGFFAR4
SCHEMBL27773869 0.85 PPARA (0.50) PPARAMAPTRXFP1PPARGBIRC5
SCHEMBL9178046 0.84 FFAR4 (0.55) PPARAALOX5FFAR4FFAR1APP
SCHEMBL14538389 0.82 PPARA (0.57) PPARASELPALOX5PPARGFFAR4
SCHEMBL7095615 0.82 PPARA (0.59) PPARASELPALOX5PPARG
SCHEMBL6943609 0.81 PPARA (0.56) PPARASELPALOX5PPARGFFAR4
SCHEMBL9180426 0.81 FFAR1 (0.57) MAPTRXFP1FFAR4FFAR1HSD17B10
SCHEMBL7415347 0.81 PPARA (0.58) PPARASELPALOX5MAPTRXFP1
SCHEMBL9259385 0.80 PPARA (0.45) PPARAALOX5MAPTRXFP1
SCHEMBL503571 0.77 PLAAT3 (0.61) PPARASELPPPARGCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426573-B1 Phenoxypropylamine derivatives or salts thereof and antiulcer agents containing the same TERUMO CORP (JP) 1995-05-24 EP disclosed
US-5037837-A 5-lipoxygenase inhibitor TERUMO KABUSHIKI KAISHA (JP) 1991-08-06 US disclosed