Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.43 |
| ▸ | TUBB | P07437 | 1/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9175204 | 0.83 | PPARA (0.58) | PPARAPOLBSMN1; SMN2ALOX5 | |
| SCHEMBL500045 | 0.82 | POLB (0.55) | POLBMAPK1SMN1; SMN2TUBB4ATUBB | |
| SCHEMBL27043019 | 0.80 | ALOX5 (0.59) | PPARATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9250363 | 0.80 | POLB (0.48) | PPARAPOLBMAPK1SMN1; SMN2TUBB4A | |
| SCHEMBL9178152 | 0.80 | PPARA (0.51) | PPARAALOX5MAPTRXFP1 | |
| SCHEMBL7095615 | 0.76 | PPARA (0.59) | PPARAPOLBALOX5 | |
| SCHEMBL9176250 | 0.76 | KDM4E (0.38) | POLBTUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL11703528 | 0.75 | PPARA (0.43) | PPARAALOX5MAPTRXFP1TNKS2 | |
| SCHEMBL29598883 | 0.75 | SELP (0.48) | PPARAMAPK1SMN1; SMN2ALOX5RXFP1 | |
| SCHEMBL9178047 | 0.75 | ALDH1A1 (0.43) | POLBSMN1; SMN2TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426573-B1 | Phenoxypropylamine derivatives or salts thereof and antiulcer agents containing the same | TERUMO CORP (JP) | 1995-05-24 | — | — | EP | disclosed |
| US-5037837-A | 5-lipoxygenase inhibitor | TERUMO KABUSHIKI KAISHA (JP) | 1991-08-06 | — | — | US | disclosed |
| EP-0426573-A2 | Phenoxypropylamine derivatives or salts thereof and antiulcer agents containing the same | TERUMO KABUSHIKI KAISHA (JP) | 1991-05-08 | — | — | EP | disclosed |