Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | GBA1 | P04062 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91726 | 0.89 | KMT2A (0.36) | KMT2AGBA1ESR1HGFACMEN1 | |
| SCHEMBL91720 | 0.84 | KMT2A (0.39) | KMT2AGBA1ESR1HGFACMEN1 | |
| SCHEMBL18636448 | 0.80 | KMT2A (0.49) | KMT2AGBA1ESR1HGFACMEN1 | |
| SCHEMBL10018721 | 0.80 | KMT2A (0.53) | KMT2AGBA1MEN1MAPTNPC1 | |
| SCHEMBL14016869 | 0.79 | ALDH1A1 (0.51) | KMT2AGBA1MEN1MAPTNPC1 | |
| SCHEMBL91717 | 0.78 | ERN1 (0.43) | KMT2AGBA1ESR1MEN1MAPT | |
| SCHEMBL14570020 | 0.77 | ALDH1A1 (0.55) | KMT2AGBA1MEN1MAPTNPC1 | |
| SCHEMBL91695 | 0.76 | ERN1 (0.47) | ESR1ABL1ERN1 | |
| SCHEMBL91745 | 0.75 | KMT2A (0.37) | KMT2AGBA1ESR1HGFACMEN1 | |
| SCHEMBL14075270 | 0.75 | RXRA (0.40) | ESR1NPC1RAB9AKDM4EABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |