1-Naphthol

1-Naphthol

SCHEMBL9178338

CCS(=O)(=O)c1cccc2ccccc12.Oc1cccc2ccccc12

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.59
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
HCRTR1 O43613 1/20 0.53
CDK2 P24941 1/20 0.49
COMT P21964 1/20 0.46
F2 P00734 3/20 0.46
PRSS1 P07477 3/20 0.46
PRSS2 P07478 3/20 0.46
PRSS3 P35030 3/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.43
ESR1 P03372 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.43
ESR2 Q92731 1/20 0.43
HTR6 P50406 2/20 0.42
KEAP1 Q14145 1/20 0.42
NFE2L2 Q16236 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL878485 0.89 CA1 (0.61) CYP1A2CA1CA2CA9HCRTR1
1-Naphthol SCHEMBL28950266 0.82 CYP1A2 (0.63) CYP1A2CA1CA2CA9HCRTR1
1-Naphthol SCHEMBL28476693 0.81 CYP1A2 (0.74) CYP1A2KDM4EGAAKMT2AALDH1A1
1-Naphthol SCHEMBL29216682 0.80 CYP1A2 (0.71) CYP1A2CA1CA2CA9HCRTR1
1-Naphthol SCHEMBL30669386 0.79 CYP1A2 (0.77) CYP1A2CA1CA2CA9HCRTR1
1-Naphthol SCHEMBL7714764 0.79 CYP1A2 (0.77) CYP1A2CA1CA2CA9HCRTR1
1-Naphthol SCHEMBL2481329 0.79 CYP1A2 (0.77) CYP1A2KDM4EGAAKMT2AALDH1A1
SCHEMBL672426 0.79 PSIP1 (0.48) CYP1A2CA1CA2CA9CDK2
SCHEMBL2703626 0.79 CA1 (0.53) CYP1A2CA1CA2CA9HCRTR1
SCHEMBL3324371 0.78 CA1 (0.57) CYP1A2CA1CA2CA9HCRTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5463031-A Printing, dyeing cellulose and organonitrogen compounds BAYER AKTIENGESELLSCHAFT (DE) 1995-10-31 US disclosed