Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 16/20 | 0.64 |
| ▸ | CYSLTR1 | Q9Y271 | 16/20 | 0.64 |
| ▸ | PPARG | P37231 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 3/20 | 0.56 |
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18590691 | 0.93 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9176648 | 0.91 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| Tipelukast SCHEMBL154898 | 0.90 | CYSLTR2 (0.78) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| Tipelukast SCHEMBL29359070 | 0.90 | CYSLTR2 (0.78) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL18609722 | 0.90 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9342993 | 0.88 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL12281318 | 0.86 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL17300445 | 0.86 | CYSLTR2 (0.54) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL17247293 | 0.85 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL17771267 | 0.85 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3139911-B1 | METHOD OF TREATING ADVANCED NON-ALCOHOLIC STEATOHEPATITIS | MEDICINOVA INC (US) | 2023-10-25 | — | — | EP | disclosed |
| US-8026282-B2 | Phenoxyalkylcarboxylic acid derivatives in the treatment of irritable bowel syndrome | MEDICINOVA, INC. (US) | 2011-09-27 | — | — | US | disclosed |
| US-20100285074-A1 | PHENOXYALKYLCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME | MEDICINOVA, INC. | 2010-11-11 | — | — | US | disclosed |
| US-7786169-B2 | Phenoxyalkycarboxylic acid derivatives in the treatment of ulcerative colitis | MEDICINOVA, INC. (US) | 2010-08-31 | — | — | US | disclosed |
| US-20090093545-A1 | PHENOXYALKYCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME OR ULCERATIVE COLITIS | MEDICINOVA, INC. | 2009-04-09 | — | — | US | disclosed |
| US-7429617-B2 | Phenoxyalkycarboxylic acid derivatives in the treatment of interstitial cystitis | MEDICINOVA, INC. (US) | 2008-09-30 | — | — | US | disclosed |
| EP-0495485-B1 | Phenoxyalkylcarboxylic acid derivatives, process of preparing the same and anti-allergic agents | KYORIN SEIYAKU KK (JP) | 1995-04-12 | — | — | EP | disclosed |
| US-5290812-A | Leukotriene antagonist as antiallergens and treatment asthma | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1994-03-01 | — | — | US | disclosed |
| EP-0495485-A2 | Phenoxyalkylcarboxylic acid derivatives, process of preparing the same and anti-allergic agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-07-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100285074-A1 | PHENOXYALKYLCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME | SI, SLC10A2, HCAR2 | CYSLTR2 78/4885CYSLTR1 157/4885PPARG 1367/4885 |
| US-20090093545-A1 | PHENOXYALKYCARBOXYLIC ACID DERIVATIVES IN THE TREATMENT OF IRRITABLE BOWEL SYNDROME OR ULCERATIVE COLITIS | SI, HCAR2, SUCNR1 | CYSLTR2 209/4885CYSLTR1 282/4885PPARG 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.