Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.54 |
| ▸ | PPARG | P37231 | 4/20 | 0.54 |
| ▸ | PPARD | Q03181 | 4/20 | 0.54 |
| ▸ | PPARA | Q07869 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12281318 | 0.94 | CYSLTR2 (0.56) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL18590691 | 0.90 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL15032724 | 0.89 | PPARG (0.60) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9176648 | 0.87 | CYSLTR2 (0.51) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL9178402 | 0.86 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL12280239 | 0.85 | PPARG (0.63) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL17771268 | 0.83 | CYSLTR2 (0.39) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL17247293 | 0.82 | CYSLTR2 (0.66) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL2419557 | 0.80 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1PPARGPPARDPPARA | |
| SCHEMBL17771267 | 0.79 | CYSLTR2 (0.50) | CYSLTR2CYSLTR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170065544-A1 | METHOD OF TREATING IDIOPATHIC PULMONARY FIBROSIS | MEDICINOVA, INC. (US) | 2017-03-09 | — | — | US | disclosed |
| US-9498458-B2 | Method of inhibiting or treating fibrosis | MEDICINOVA, INC. (US) | 2016-11-22 | — | — | US | disclosed |
| US-20150342913-A1 | METHOD OF INHIBITING OR TREATING FIBROSIS | MEDICINOVA, INC. | 2015-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150342913-A1 | METHOD OF INHIBITING OR TREATING FIBROSIS | MMP1, COL1A1, CCL11 | CYSLTR2 402/4885CYSLTR1 237/4885PPARG 931/4885 |
| US-20170065544-A1 | METHOD OF TREATING IDIOPATHIC PULMONARY FIBROSIS | CCL11, CFTR, ELANE | CYSLTR2 301/4885CYSLTR1 229/4885PPARG 793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.