Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYB | P10242 | 14/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538170 | 0.85 | MYB (0.82) | MYBMAPTKDM4ELMNACYP1A2 | |
| SCHEMBL8113327 | 0.83 | MYB (0.75) | MYBMAPTKDM4ELMNAHPGD | |
| SCHEMBL8112346 | 0.81 | MPO (0.56) | MYBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL8117263 | 0.81 | MYB (0.61) | MYBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL8113346 | 0.79 | MYB (0.77) | MYBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL8112822 | 0.79 | MYB (0.58) | MYBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL8112856 | 0.79 | KDM4E (0.73) | MYBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL8808921 | 0.78 | MAPT (0.53) | MYBMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL8538804 | 0.76 | MYB (0.84) | MYBMAPTKDM4ELMNACYP1A2 | |
| SCHEMBL4320517 | 0.75 | TUBB4A (0.67) | MYBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434160-A | Autoimmune diseases; prevention of excess cell proliferation or enzyme release | LILLY INDUSTRIES LIMITED (GB) | 1995-07-18 | — | — | US | disclosed |
| EP-0599514-A2 | Pyranoquinoline derivatives as inhibitors of cell proliferation | LILLY INDUSTRIES LIMITED (GB) | 1994-06-01 | — | — | EP | disclosed |