Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 8/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30447964 | 0.79 | PARP1 (0.38) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL3840448 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL9180091 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL30620546 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL10590809 | 0.72 | NPC1 (0.44) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL9178772 | 0.71 | RXRA (0.40) | ALDH1A1MAPTTSHRHSD17B10PARP1 | |
| SCHEMBL22031788 | 0.70 | PARP1 (0.54) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL27695187 | 0.69 | PARP1 (0.51) | PARP1PDK2IRAK4PARP2 | |
| SCHEMBL28786237 | 0.68 | PARP1 (0.56) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL21911671 | 0.68 | PARP1 (0.54) | PARP1PARP2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | claimed |