SCHEMBL9180809

SCHEMBL9180809

C=COCC1CCC(COC(=O)/C=C\C(=O)OCC2CCC(COC=C)CC2)CC1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
HCAR2 Q8TDS4 1/20 0.31
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9180814 1.00 LMNA (0.33) LMNAMAPTCACNA1BAPBA1HCAR2
SCHEMBL278984 0.89 TSHR (0.39) LMNA
SCHEMBL2526794 0.81 LMNA (0.51) LMNA
SCHEMBL4066822 0.81 JAK2 (0.33) LMNA
SCHEMBL14488382 0.79
SCHEMBL1155328 0.79
SCHEMBL238829 0.79
SCHEMBL22187599 0.79
SCHEMBL2523203 0.79 LMNA (0.45) LMNA
SCHEMBL217791 0.79 LMNA (0.45) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0549588-B1 VINYL ETHER BASED OPTICAL FIBER COATINGS ALLIED SIGNAL INC (US) 1995-08-16 EP disclosed
EP-0549588-A1 VINYL ETHER BASED OPTICAL FIBER COATINGS. ALLIED SIGNAL INC (US) 1993-07-07 EP disclosed
US-5139872-A Polyetherurethanes and polyesterurethanes endcapped with hydroxyvinyl ethers reacted with vinyl ether terminated ester or vinyl ether ALLIED-SIGNAL INC. (US) 1992-08-18 US disclosed
WO-1992004388-A1 VINYL ETHER BASED OPTICAL FIBER COATINGS ALLIED-SIGNAL INC. (US) 1992-03-19 WO disclosed