Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278690 | 0.84 | ALDH1A1 (0.49) | LMNATHRATHRBALDH1A1 | |
| SCHEMBL6256094 | 0.84 | — | — | |
| SCHEMBL5696892 | 0.84 | ALDH1A1 (0.43) | JAK2JAK1TYK2JAK3LMNA | |
| SCHEMBL17029138 | 0.84 | ALDH1A1 (0.43) | JAK2JAK1TYK2JAK3LMNA | |
| SCHEMBL5676446 | 0.83 | JAK2 (0.34) | JAK2JAK1TYK2JAK3LMNA | |
| SCHEMBL2526794 | 0.81 | LMNA (0.51) | LMNAALDH1A1 | |
| SCHEMBL9180809 | 0.81 | LMNA (0.33) | LMNA | |
| SCHEMBL9180814 | 0.81 | LMNA (0.33) | LMNA | |
| SCHEMBL278984 | 0.81 | TSHR (0.39) | LMNATHRATHRBALDH1A1HSD17B10 | |
| SCHEMBL23177333 | 0.81 | TSHR (0.41) | JAK2JAK1TYK2JAK3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785582-B2 | Vinylozy group-containing vinyl polymer | NIPPON CARBIDE INDUSTRIES CO., LTD. (JP) | 2014-07-22 | — | — | US | claimed |
| US-20130245189-A1 | VINYLOZY GROUP-CONTAINING VINYL POLYMER | NIPPON CARBIDE INDUSTRIES CO., INC. (JP) | 2013-09-19 | — | — | US | claimed |
| US-8785582-B2 | Vinylozy group-containing vinyl polymer | NIPPON CARBIDE INDUSTRIES CO., LTD. (JP) | 2014-07-22 | — | — | US | disclosed |
| US-20130245189-A1 | VINYLOZY GROUP-CONTAINING VINYL POLYMER | NIPPON CARBIDE INDUSTRIES CO., INC. (JP) | 2013-09-19 | — | — | US | disclosed |
| JP-2009096836-A | 1-ACETOXYMETHYL-4-CYCLOHEXYLMETHYL VINYL ETHER | NIPPON CARBIDE IND CO INC | 2009-05-07 | — | — | JP | disclosed |