SCHEMBL278984

SCHEMBL278984

C=COCC1CCC(COC(=O)C=C)CC1

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.39
ALDH1A1 P00352 4/20 0.39
TP53 P04637 3/20 0.39
HIF1A Q16665 3/20 0.39
CYP3A4 P08684 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HPGD P15428 1/20 0.36
THRB P10828 3/20 0.33
LMNA P02545 1/20 0.33
THRA P10827 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL421446 0.90 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6557409 0.90 TSHR (0.46) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3678063 0.90
SCHEMBL9180809 0.89 LMNA (0.33) LMNA
SCHEMBL9180814 0.89 LMNA (0.33) LMNA
SCHEMBL33527907 0.88 TSHR (0.36) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL15623980 0.87 TSHR (0.38) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL23837211 0.85 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL1963100 0.85 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL12154290 0.85 TSHR (0.42) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method SEIKO EPSON CORP (JP) 2026-04-02 US disclosed
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus SEIKO EPSON CORP (JP) 2026-04-02 US disclosed
EP-3980510-B1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2023-11-08 EP disclosed
EP-3802730-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2023-04-19 EP disclosed
US-20230068853-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2023-03-02 US disclosed
WO-2022122780-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2022-06-16 WO disclosed
US-11353751-B2 Double layer liquid crystal device and process of manufacture MERCK PATENT GMBH (DE) 2022-06-07 US disclosed
US-20210096431-A1 Double Layer Liquid Crystal Device and Process of Manufacture MERCK PATENT GMBH (DE) 2021-04-01 US disclosed
WO-2020245084-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2020-12-10 WO disclosed
EP-3529332-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2020-11-25 EP disclosed
EP-2199273-A1 Polymerizable photoinitiators and radiation curable compositions AGFA Graphics NV (BE) 2010-06-23 EP disclosed
US-20100041845-A1 HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-02-18 US disclosed
US-20100041845-A1 HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF DESIGNER MOLECULES, INC. (US) 2010-02-18 US disclosed
US-RE40847-E1 Ink compositions for ink jet printing AGFA-GEVAERT (BE) 2009-07-14 US disclosed
US-RE40847-E1 Ink compositions for ink jet printing AGFA-GEVAERT (BE) 2009-07-14 US disclosed
WO-2009053283-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2009-04-30 WO disclosed
EP-2053100-A1 Radiation curable inkjet printing methods Agfa Graphics N.V. (BE) 2009-04-29 EP disclosed
US-20080227927-A1 VINYL ETHERS AND COMPOSITIONS CONTAINING THEM PPG INDUSTRIES OHIO, INC. (US) 2008-09-18 US disclosed
US-7411033-B2 Vinyl ethers and compositions containing them PPG INDUSTRIES OHIO, INC. (US) 2008-08-12 US disclosed
US-20070293652-A1 VINYL ETHERS AND COMPOSITIONS CONTAINING THEM PPG INDUSTRIES OHIO, INC. 2007-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260092190-A1 Radiation Curable Ink Composition For Ink Jet And Recording Apparatus KAT8, TAS2R8, NLRP3 TSHR 3114/4885ALDH1A1 207/4885TP53 1037/4885
US-20230068853-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY CXCR1, PYM1, F11 TSHR 3248/4885ALDH1A1 2963/4885TP53 925/4885
US-20100041845-A1 HETERO-FUNCTIONAL COMPOUNDS AND METHODS FOR USE THEREOF C9, C3AR1, C1S TSHR 4373/4885ALDH1A1 1455/4885TP53 3471/4885
US-20260092188-A1 Radiation Curable Ink Composition For Ink Jet And Ink Jet Recording Method JAK1, EED, PI4KA TSHR 4124/4885ALDH1A1 1184/4885TP53 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.