Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.61 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 4/20 | 0.49 |
| ▸ | DRD4 | P21917 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183697 | 0.84 | P2RX7 (0.59) | P2RX7 | |
| SCHEMBL9181173 | 0.83 | P2RX7 (0.57) | P2RX7DRD3 | |
| SCHEMBL9180280 | 0.80 | MEN1 (0.60) | P2RX7DRD2DRD3HTR7 | |
| SCHEMBL9187308 | 0.75 | LMNA (0.56) | P2RX7 | |
| SCHEMBL16226519 | 0.75 | HDAC4 (0.69) | P2RX7DRD2DRD3DRD4 | |
| SCHEMBL9184019 | 0.73 | LMNA (0.47) | P2RX7 | |
| SCHEMBL9633550 | 0.73 | HTR1A (0.64) | DRD2DRD3DRD4HTR2AHTR7 | |
| SCHEMBL9183346 | 0.73 | ABCB1 (0.74) | — | |
| SCHEMBL28309625 | 0.72 | CYP19A1 (0.57) | — | |
| SCHEMBL9186320 | 0.72 | ABCB1 (0.59) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |