SCHEMBL9181548

SCHEMBL9181548

[SiH3]CC(c1ccc(N(c2ccccc2)c2ccccc2)cc1)(c1ccc(N(c2ccccc2)c2ccccc2)cc1)c1ccc(N(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
CYP2D6 P10635 2/20 0.45
KDM4E B2RXH2 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
MAPT P10636 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
CRHBP P24387 1/20 0.38
ATM Q13315 1/20 0.38
CRHR2 Q13324 1/20 0.38
TLR9 Q9NR96 1/20 0.38
KIF11 P52732 4/20 0.33
HDAC6 Q9UBN7 1/20 0.32
NR1H2 P55055 3/20 0.32
NR1H3 Q13133 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9179222 0.81 KIF11 (0.44) ALDH1A1L3MBTL1TDP1CYP2D6KDM4E
SCHEMBL9319485 0.79 KIF11 (0.46) ALDH1A1CYP1A2CYP2C9CYP2C19KIF11
SCHEMBL13721260 0.74 ALDH1A1 (0.72) ALDH1A1L3MBTL1TDP1CYP2D6KDM4E
SCHEMBL13720763 0.74 ALDH1A1 (0.72) ALDH1A1L3MBTL1TDP1CYP2D6KDM4E
SCHEMBL302043 0.74 ALDH1A1 (0.72) ALDH1A1L3MBTL1TDP1CYP2D6KDM4E
SCHEMBL17087772 0.74 ALDH1A1 (0.72) ALDH1A1L3MBTL1TDP1CYP2D6KDM4E
SCHEMBL12333623 0.74 ALDH1A1 (0.72) ALDH1A1L3MBTL1TDP1CYP2D6KDM4E
SCHEMBL2389596 0.74 ALDH1A1 (0.72) ALDH1A1L3MBTL1TDP1CYP2D6KDM4E
SCHEMBL36869 0.74 ALDH1A1 (0.72) ALDH1A1L3MBTL1TDP1CYP2D6KDM4E
SCHEMBL6123843 0.74 ALDH1A1 (0.72) ALDH1A1L3MBTL1TDP1CYP2D6KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3264593-A None JP disclosed
EP-0446895-B1 Novel organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it KAO CORP (JP) 1995-08-02 EP disclosed
US-5352554-A Organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it KAO CORPORATION (JP) 1994-10-04 US disclosed
US-5187310-A Sensitivity, durability KAO CORPORATION (JP) 1993-02-16 US disclosed
JP-H03264593-A NOVEL SILYLATED TRIARYLAMINE COMPOUND AND PREPARATION THEREOF, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR CONTAINING SAME KAO CORP 1991-11-25 JP disclosed
EP-0446895-A1 Novel organic silicon compound, method of its production, and photoreceptor for electrophotography incorporating it Kao Corporation (JP) 1991-09-18 EP disclosed