Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9465763 | 1.00 | HTR2C (0.38) | HTR2C | |
| SCHEMBL9465608 | 0.91 | — | — | |
| SCHEMBL9174170 | 0.91 | — | — | |
| SCHEMBL1037294 | 0.89 | — | — | |
| SCHEMBL9178238 | 0.89 | — | — | |
| SCHEMBL9176453 | 0.87 | DRD2 (0.45) | — | |
| SCHEMBL9467335 | 0.87 | DRD2 (0.45) | — | |
| SCHEMBL9177231 | 0.86 | DRD4 (0.46) | — | |
| SCHEMBL9180749 | 0.86 | DRD4 (0.46) | — | |
| SCHEMBL9179387 | 0.85 | SIGMAR1 (0.53) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490772-B1 | 1,4-Disubstituted piperazines, their process of preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-07-26 | — | — | EP | disclosed |