Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.72 |
| ▸ | NPC1 | O15118 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.58 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.58 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.58 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879030 | 0.89 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL10943445 | 0.89 | RAB9A (0.88) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL9645677 | 0.87 | RAB9A (0.74) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL2249088 | 0.86 | CA1 (0.63) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9185209 | 0.85 | RAB9A (0.70) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL9181995 | 0.84 | SMN1; SMN2 (0.79) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL4724997 | 0.84 | SMN1; SMN2 (1.00) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL9181179 | 0.82 | SMN1; SMN2 (0.50) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL6707294 | 0.82 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2GAAMEN1 | |
| SCHEMBL9449917 | 0.82 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | claimed |
| US-5378728-A | Benzoic acid derivatives as antidiabetic agents | SANDOZ LTD. (CH) | 1995-01-03 | — | — | US | disclosed |