Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | GAA | P10253 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.59 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.59 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.59 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.59 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879030 | 0.91 | RAB9A (0.88) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL10943445 | 0.91 | RAB9A (0.88) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL571045 | 0.87 | CA12 (0.63) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL9182180 | 0.87 | RAB9A (0.72) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL14706883 | 0.86 | SMN1; SMN2 (0.68) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL196507 | 0.86 | SMN1; SMN2 (0.61) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL4724997 | 0.85 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2NPC1GAAMAPT | |
| SCHEMBL4611487 | 0.84 | HDAC3 (0.71) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL3882727 | 0.84 | HDAC3 (0.71) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL9646009 | 0.84 | RAB9A (0.53) | RAB9ASMN1; SMN2NPC1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346713-B1 | BENZAMIDINES USEFUL AS ULTRAVIOLET LIGHT ABSORBERS | L. GIVAUDAN & CIE Société Anonyme (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-5011628-A | N,N'-diarylbenzamidines useful as ultraviolet light absorbers | GIVAUDAN CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |