SCHEMBL9183153

SCHEMBL9183153

Cc1ccc(C(=O)O)c(O)c1C.[Cr]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.55
ALDH1A1 P00352 1/20 0.55
HPGD P15428 1/20 0.55
HSD17B10 Q99714 1/20 0.55
GRM1 Q13255 1/20 0.53
SELL P14151 1/20 0.50
SELP P16109 1/20 0.50
TDP1 Q9NUW8 3/20 0.44
MAPT P10636 2/20 0.44
KMT2A Q03164 3/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2C9 P11712 2/20 0.43
MCL1 Q07820 2/20 0.43
LDHA P00338 1/20 0.42
HAAO P46952 1/20 0.42
CYP1A2 P05177 2/20 0.42
HMGB1 P09429 1/20 0.41
CXCL12 P48061 1/20 0.41
MMP2 P08253 2/20 0.41
ALB P02768 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL317576 0.98 ALDH1A1 (0.57) KDM4EALDH1A1HPGDHSD17B10GRM1
SCHEMBL30149140 0.98 ALDH1A1 (0.57) KDM4EALDH1A1HPGDHSD17B10GRM1
Bicarbonate SCHEMBL4612195 0.96 KDM4E (0.55) KDM4EALDH1A1HPGDHSD17B10GRM1
SCHEMBL30396337 0.96 KDM4E (0.55) KDM4EALDH1A1HPGDHSD17B10GRM1
SCHEMBL2362285 0.82 GRM1 (0.46) KDM4EALDH1A1HPGDHSD17B10GRM1
SCHEMBL4132985 0.82 KMT2A (0.46) KDM4EALDH1A1HPGDHSD17B10GRM1
SCHEMBL30083685 0.82 ALDH1A1 (0.65) KDM4EALDH1A1HPGDHSD17B10GRM1
SCHEMBL857301 0.82 ALDH1A1 (0.65) KDM4EALDH1A1HPGDHSD17B10GRM1
SCHEMBL27785277 0.82 HPGD (0.50) KDM4EALDH1A1HPGDHSD17B10GRM1
SCHEMBL5303538 0.81 KMT2A (0.70) KDM4EALDH1A1HPGDHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0291930-B1 A toner for developing electrostatic charge image CANON KK (JP) 1995-08-02 EP disclosed
US-4857432-A BLEND OF BINDER, MAGNETIC POWDER AND COORDINATION COMPLEX CANON KABUSHIKI KAISHA (JP) 1989-08-15 US disclosed
EP-0291930-A2 A toner for developing electrostatic charge image CANON KABUSHIKI KAISHA (JP) 1988-11-23 EP disclosed