Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 3/20 | 0.50 |
| ▸ | CTSV | O60911 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9182668 | 0.84 | AKR1C3 (0.62) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8390211 | 0.83 | CTSV (0.66) | MEN1KMT2ACDC25BCTSVCTSL | |
| SCHEMBL12149845 | 0.74 | MEN1 (0.60) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1375050 | 0.74 | KMT2A (0.76) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL12149855 | 0.73 | PARP10 (0.63) | MEN1KMT2ASMN1; SMN2HPGDPARP10 | |
| SCHEMBL7911320 | 0.73 | PARP10 (0.63) | MEN1KMT2ASMN1; SMN2HPGDPARP10 | |
| SCHEMBL12149856 | 0.73 | PARP10 (0.60) | MEN1KMT2AKDM4EHPGDPARP10 | |
| SCHEMBL12151682 | 0.73 | FDPS (0.64) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1374597 | 0.72 | FDPS (0.61) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL1147050 | 0.72 | CDC25B (0.71) | MEN1KMT2ALMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5420123-A | Dibenzodiazepine endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-05-30 | — | — | US | disclosed |