Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 5/20 | 0.66 |
| ▸ | CTSL | P07711 | 5/20 | 0.66 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.51 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183441 | 0.83 | MEN1 (0.52) | CTSVCTSLMEN1CASP3KMT2A | |
| SCHEMBL31504338 | 0.82 | CTSV (0.62) | CTSVCTSLSIRT2CHRM4CHRM3 | |
| SCHEMBL21617230 | 0.82 | CTSV (0.62) | CTSVCTSLSIRT2CHRM4CHRM3 | |
| SCHEMBL5495792 | 0.81 | MAOB (0.60) | CTSVCTSLMEN1KMT2AMCL1 | |
| SCHEMBL8391099 | 0.81 | AKR1C3 (0.71) | CTSVCTSLSIRT2MEN1KMT2A | |
| SCHEMBL10833797 | 0.80 | SIRT2 (0.80) | CTSVCTSLSIRT2CHRM4CHRM3 | |
| SCHEMBL10983488 | 0.80 | CTSV (1.00) | CTSVCTSLSIRT2MEN1KMT2A | |
| SCHEMBL474131 | 0.78 | NR4A2 (0.57) | CTSVCTSLMEN1KMT2ACDC25B | |
| SCHEMBL11650244 | 0.78 | BRD4 (0.58) | MEN1KMT2AMAOB | |
| SCHEMBL4853225 | 0.78 | LNPEP (0.48) | MEN1KMT2AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919780-A | ANTICANCER AGENT, OR RESTENOSIS INHIBITING AGENT OR ANTIPSORIASIS AGENT OR ANTIVIRAL AGENT | WARNER LAMBERT COMPANY (US) | 1999-07-06 | — | — | US | disclosed |
| WO-1997000252-A1 | TRICYCLIC INHIBITORS OF PROTEIN FARNESYLTRANSFERASE | WARNER-LAMBERT COMPANY (US) | 1997-01-03 | — | — | WO | disclosed |
| US-5420123-A | Dibenzodiazepine endothelin antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-05-30 | — | — | US | disclosed |