Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | SI | P14410 | 4/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91982 | 0.87 | RARA (0.38) | RARARARBERN1MGAMGAA | |
| SCHEMBL4422884 | 0.85 | FFAR1 (0.32) | PTPN7DUSP3FFAR1 | |
| SCHEMBL3624809 | 0.82 | GAA (0.43) | ERN1MGAMGAASIMGAM2 | |
| SCHEMBL13673199 | 0.81 | ERN1 (0.33) | ERN1MGAMGAASIMGAM2 | |
| SCHEMBL13863856 | 0.80 | FFAR1 (0.34) | RARARARBPTPN7DUSP3L3MBTL1 | |
| SCHEMBL4413674 | 0.79 | CYP1A1 (0.40) | PTPN7DUSP3L3MBTL1CYP1A1CYP1B1 | |
| SCHEMBL19801830 | 0.78 | RARA (0.43) | RARARARBERN1PTPN7DUSP3 | |
| SCHEMBL91910 | 0.78 | ADORA3 (0.35) | RARARARBMGAMGAASI | |
| SCHEMBL4415939 | 0.77 | FFAR1 (0.32) | FFAR1 | |
| SCHEMBL14075505 | 0.77 | FFAR1 (0.35) | RARARARBGAAL3MBTL1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129002-B2 | Compounds for use in liquid crystal media | MERCK PATENT GMBH (DE) | 2012-03-06 | — | — | US | disclosed |
| US-7531106-B2 | Mesogenic compounds, medium for electro-optical displays and electro-optical display | MERCK PATENT GMBH (DE) | 2009-05-12 | — | — | US | disclosed |