Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.43 |
| ▸ | MGAM | O43451 | 5/20 | 0.43 |
| ▸ | SI | P14410 | 5/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16575404 | 0.91 | ADORA3 (0.51) | MAPTKMT2AADORA3MEN1LTA4H | |
| SCHEMBL13863862 | 0.88 | CSNK2A1 (0.39) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL91982 | 0.86 | RARA (0.38) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL13186042 | 0.82 | LMNA (0.44) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL91835 | 0.82 | RARA (0.36) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL14640143 | 0.81 | LMNA (0.43) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL13186040 | 0.81 | LMNA (0.43) | GAAMGAMSIMGAM2SMN1; SMN2 | |
| SCHEMBL91910 | 0.80 | ADORA3 (0.35) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL14075505 | 0.79 | FFAR1 (0.35) | GAAALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL91924 | 0.78 | PTPN11 (0.41) | GAARAB9ANPC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906662-B1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2020-04-01 | — | — | EP | disclosed |
| US-20150303397-A1 | INORGANIC BARRIER LAYERS | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150303397-A1 | INORGANIC BARRIER LAYERS | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150270489-A1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| US-20150270489-A1 | EMITTER AND HOSTS WITH AROMATIC UNITS | MERCK PATENT GMBH (DE) | 2015-09-24 | — | — | US | disclosed |
| EP-1739151-B1 | Mesogenic compounds, liquid crystal medium and liquid display | MERCK PATENT GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-1739151-B1 | Mesogenic compounds, liquid crystal medium and liquid display | MERCK PATENT GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-1739151-A1 | Mesogenic compounds, liquid crystal medium and liquid display | MERCK PATENT GmbH (DE) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739151-A1 | Mesogenic compounds, liquid crystal medium and liquid display | MERCK PATENT GmbH (DE) | 2007-01-03 | — | — | EP | disclosed |