Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDE6D | O43924 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185538 | 0.95 | L3MBTL1 (0.50) | L3MBTL1HPGDLMNAALDH1A1PKM | |
| SCHEMBL9184179 | 0.90 | L3MBTL1 (0.52) | L3MBTL1HPGDLMNAALDH1A1PKM | |
| SCHEMBL9187705 | 0.83 | ALDH1A1 (0.52) | HPGDALDH1A1PTGS2TSHR | |
| SCHEMBL16392966 | 0.79 | L3MBTL1 (0.57) | L3MBTL1HPGDLMNAALDH1A1PKM | |
| SCHEMBL7632891 | 0.78 | L3MBTL1 (0.56) | L3MBTL1HPGDLMNAALDH1A1PKM | |
| SCHEMBL9188610 | 0.78 | L3MBTL1 (0.56) | L3MBTL1HPGDLMNAALDH1A1PKM | |
| SCHEMBL20216016 | 0.77 | L3MBTL1 (0.58) | L3MBTL1HPGDLMNAALDH1A1PKM | |
| SCHEMBL21985460 | 0.76 | L3MBTL1 (0.57) | L3MBTL1HPGDLMNAALDH1A1PKM | |
| SCHEMBL19976649 | 0.76 | L3MBTL1 (0.57) | L3MBTL1HPGDLMNAALDH1A1PKM | |
| SCHEMBL23585046 | 0.76 | L3MBTL1 (0.59) | L3MBTL1HPGDLMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0576475-B1 | ISOINDOLES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO SPA (IT) | 1995-09-20 | — | — | EP | disclosed |
| US-5376673-A | Vasodilation | ITALFARMACO S.P.A. (IT) | 1994-12-27 | — | — | US | disclosed |
| EP-0576475-A1 | ISOINDOLES HAVING CARDIOVASCULAR ACTIVITY. | ITALFARMACO SPA (IT) | 1994-01-05 | — | — | EP | disclosed |
| WO-1992016506-A1 | ISOINDOLES HAVING CARDIOVASCULAR ACTIVITY | ITALFARMACO S.P.A. (IT) | 1992-10-01 | — | — | WO | disclosed |