Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9070259 | 0.87 | HTR2C (0.53) | HTR2CHTR2BHPGDRAB9ANPC1 | |
| SCHEMBL15947634 | 0.79 | SNCA (0.48) | HTR2CHTR2BCNR2HPGDMAPT | |
| SCHEMBL9131641 | 0.76 | APP (0.56) | CNR2APPHPGDRAB9ANPC1 | |
| SCHEMBL9133103 | 0.75 | APP (0.52) | CNR2APPHPGDRAB9ANPC1 | |
| SCHEMBL9131768 | 0.72 | APP (0.53) | CNR2APPRAB9ANPC1MAPT | |
| SCHEMBL9183847 | 0.72 | CNR2 (0.58) | CNR2APPHPGDRAB9ANPC1 | |
| SCHEMBL8084097 | 0.72 | HTR2C (0.48) | HTR2CHTR2BCNR2HPGDRAB9A | |
| SCHEMBL9184573 | 0.71 | APP (0.51) | CNR2APPHPGDRAB9ANPC1 | |
| SCHEMBL15947627 | 0.71 | NCF1 (0.54) | HPGDRAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL9130686 | 0.70 | APP (0.68) | APPHPGDRAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476645-B1 | Calcium uptake inhibitors | MERRELL DOW PHARMA (US) | 1995-09-06 | — | — | EP | disclosed |