Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 5/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465411 | 0.87 | CALM1 (0.44) | LMNATSHRALDH1A1 | |
| SCHEMBL7665824 | 0.83 | — | — | |
| SCHEMBL7701042 | 0.81 | — | — | |
| SCHEMBL455750 | 0.81 | — | — | |
| SCHEMBL9529885 | 0.81 | — | — | |
| SCHEMBL5851796 | 0.81 | — | — | |
| SCHEMBL20486245 | 0.81 | — | — | |
| SCHEMBL20486225 | 0.81 | TAAR1 (0.37) | TAAR1 | |
| SCHEMBL27389409 | 0.79 | PNMT (0.41) | LMNATSHRPNMTTAAR1DPP4 | |
| SCHEMBL12815531 | 0.79 | IDO1 (0.42) | LMNAIDO1PNMTTAAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0455587-B1 | New polymers and hard gas-permeable contact lenses made therefrom | CIBA GEIGY AG (CH) | 1995-07-19 | — | — | EP | disclosed |
| US-5264878-A | Polymers and hard, gas-permeable contact lenses made therefrom | CIBA-GEIGY CORPORATION (US) | 1993-11-23 | — | — | US | disclosed |
| US-5196493-A | Siloxane monvinyl and oligonvinyl components with fluoroacrylate and hydrophobic vinyl component having bulky hydrocarbon radical | CIBA-GEIGY CORPORATION (US) | 1993-03-23 | — | — | US | disclosed |
| EP-0455587-A1 | New polymers and hard gas-permeable contact lenses made therefrom | CIBA-GEIGY AG (CH) | 1991-11-06 | — | — | EP | disclosed |
| EP-0000507-B1 | PROCESS FOR THE PRODUCTION OF HYDROGELS IN THE FORM OF SPHERICALLY SHAPED BEADS WITH LARGER DIAMETERS | CIBA-GEIGY AG (CH) | 1982-09-29 | — | — | EP | disclosed |
| US-4304591-A | A HIGH-STRENGTH GEL OF MALEIMIDE-MODIFIED POLYOXYPROPYLENE OR -TETRAMETHYLENE GLYCOL CROSSLINKED BY A WATER-SOLUBLE OLEFIN; SUSTAINED RELEASE | CIBA-GEIGY CORPORATION (US) | 1981-12-08 | — | — | US | disclosed |
| US-4277582-A | MEMBRANES AND CARRIERS FOR SUSTAINED RELEASE | CIBA-GEIGY CORPORATION (US) | 1981-07-07 | — | — | US | disclosed |
| US-4224427-A | HYDROPHILIC MONOMER, POLYOLEFINIC MACROMER CROSSLINKER, METAL HYDROXIDE GEL | CIBA-GEIGY CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4192827-A | IN A DELAMINATED MATRIX OF A TRANSITITION METAL DICHALCOGENIDE | CIBA-GEIGY CORPORATION (US) | 1980-03-11 | — | — | US | disclosed |
| US-4177056-A | CROSSLINKED; SUSTAINED RELEASE | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |
| EP-0000507-A1 | Process for the production of hydrogels in the form of spherically shaped beads with larger diameters | CIBA-GEIGY AG (CH) | 1979-02-07 | — | — | EP | disclosed |
| US-4136250-A | CROSSLINKED, ADDITION MONOMER OR POLYMER | CIBA-GEIGY CORPORATION (US) | 1979-01-23 | — | — | US | disclosed |