Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4838631 | 0.81 | ADRA2B (0.33) | ADRA2BADRA2C | |
| SCHEMBL5611771 | 0.76 | SCN4A (0.33) | CA2ALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL7711448 | 0.74 | ALDH1A1 (0.37) | TDP1ALDH1A1TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL15911739 | 0.74 | ALDH1A1 (0.33) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL29012836 | 0.74 | ADRA2B (0.36) | CA2TDP1ATMALDH1A1TSHR | |
| SCHEMBL6527778 | 0.74 | ADRA2B (0.36) | CA2TDP1ATMALDH1A1TSHR | |
| SCHEMBL25059139 | 0.71 | SMN1; SMN2 (0.48) | CA2ALDH1A1ALOX12CYP1A2HSD17B10 | |
| SCHEMBL10650288 | 0.70 | CA2 (0.48) | CA2TDP1ATMGABRA1GABRB2 | |
| SCHEMBL25296963 | 0.69 | CA2 (0.43) | CA2TDP1GABRA1GABRB2ALDH1A1 | |
| SCHEMBL31438691 | 0.69 | SMN1; SMN2 (0.47) | CA2ALDH1A1ALOX12CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0463862-B1 | Aromatic vinyl ether compounds and compositions, and method of making the same | LOCTITE CORP (US) | 1995-08-09 | — | — | EP | disclosed |
| EP-0463862-A2 | Aromatic vinyl ether compounds and compositions, and method of making the same | LOCTITE CORPORATION (US) | 1992-01-02 | — | — | EP | disclosed |
| US-5070117-A | COATINGS, ADHESIVES, SEALS | LOCTITE CORPORATION (US) | 1991-12-03 | — | — | US | disclosed |
| US-5004842-A | Aromatic vinyl ether compounds and compositions, and method of making the same | LOCTITE CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |