Glycolic Acid

Glycolic Acid

SCHEMBL9185367

CCCCOC(O)C(=O)O.O=C(O)CO.O=C(O)CO

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PLA2G4B P0C869 1/20 0.39
GPR84 Q9NQS5 7/20 0.38
FFAR1 O14842 2/20 0.38
ALDH1A1 P00352 1/20 0.38
AKR1B1 P15121 1/20 0.35
ATM Q13315 1/20 0.35
CA2 P00918 1/20 0.35
MAPK1 P28482 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
HCAR2 Q8TDS4 1/20 0.35
TP53 P04637 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycolic Acid SCHEMBL5359995 0.98 PLA2G4B (0.38) PLA2G4BGPR84FFAR1ALDH1A1AKR1B1
SCHEMBL15746384 0.92 GPR84 (0.43) PLA2G4BGPR84FFAR1ALDH1A1ATM
SCHEMBL11150083 0.84 GPR84 (0.50) PLA2G4BGPR84FFAR1HCAR2TP53
SCHEMBL3345590 0.84 GPR84 (0.50) PLA2G4BGPR84FFAR1HCAR2TP53
Glycolic Acid SCHEMBL10336215 0.79 FFAR3 (0.33) GPR84FFAR1TP53TSHR
SCHEMBL11040557 0.79
Glycolic Acid SCHEMBL6246379 0.74 TSHR (0.61) GPR84FFAR1ALDH1A1AKR1B1ATM
SCHEMBL27323286 0.74 ALDH1A1 (0.41) PLA2G4BALDH1A1ATMHCAR2TP53
SCHEMBL2979038 0.74 ATM (0.41) PLA2G4BGPR84FFAR1ALDH1A1ATM
Ethylene Glycol SCHEMBL3732641 0.74 ATM (0.37) PLA2G4BGPR84FFAR1ALDH1A1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0388448-B1 MASS TREATMENT OF CELLULOSIC MATERIALS LITHIUM CORP (US) 1995-07-26 EP claimed
EP-0388448-A1 MASS TREATMENT OF CELLULOSIC MATERIALS. LITHIUM CORP (US) 1990-09-26 EP claimed
WO-1990003466-A1 MASS TREATMENT OF CELLULOSIC MATERIALS LITHIUM CORPORATION OF AMERICA (US) 1990-04-05 WO claimed
EP-0388448-B1 MASS TREATMENT OF CELLULOSIC MATERIALS LITHIUM CORP (US) 1995-07-26 EP disclosed
WO-1993025305-A1 MASS CELLULOSE DEACIDIFICATION PROCESS FMC CORPORATION (US) 1993-12-23 WO disclosed
US-5208072-A Deacidification of paper with hydrocarbon or halohydrocarbon solutions with magnesium and/or zinc alkoxyalkoxides and carbon dioxide FMC CORPORATION (US) 1993-05-04 US disclosed
US-5104997-A Deacidification using magnesium and(or) zinc alkoxyalkoxide FMC CORPORATION (US) 1992-04-14 US disclosed