Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27697796 | 0.91 | DNM1 (0.47) | PLA2G4BTSHRDNM1SPHK1USP2 | |
| SCHEMBL27522240 | 0.91 | DNM1 (0.47) | PLA2G4BTSHRDNM1SPHK1USP2 | |
| SCHEMBL15746384 | 0.81 | GPR84 (0.43) | ALDH1A1PLA2G4BTSHRTP53HCAR2 | |
| SCHEMBL14231526 | 0.81 | ALDH1A1 (0.38) | ALDH1A1PLA2G4BTSHRADRB2ADRB1 | |
| SCHEMBL27338862 | 0.78 | SMN1; SMN2 (0.32) | ALDH1A1TSHR | |
| SCHEMBL17663532 | 0.77 | TSHR (0.39) | ALDH1A1PLA2G4BTSHRADRB2ADRB1 | |
| SCHEMBL27660690 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL14975586 | 0.76 | TSHR (0.42) | ALDH1A1TSHRADRB2ADRB1ADRB3 | |
| SCHEMBL1053701 | 0.76 | — | — | |
| SCHEMBL808427 | 0.76 | TSHR (0.42) | ALDH1A1TSHRADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1029227-C | Composition for denatured denaturation or protection agent for nerve cell and process for preparing benzene derivatives used for composition | OTSUKA PHARMA CO LTD (JP) | 1995-07-05 | — | — | CN | disclosed |
| CN-1046529-A | Carbostyril derivative | OTSUKA PHARMA CO LTD (JP) | 1990-10-31 | — | — | CN | disclosed |
| CN-1044807-A | Neurocyte sex change reparation or protective material are with composition and the preparation method that is used for the benzene derivative of said composition | OTSUKA PHARMA CO LTD (JP) | 1990-08-22 | — | — | CN | disclosed |