Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.69 |
| ▸ | HTR7 | P34969 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 3/20 | 0.60 |
| ▸ | DRD3 | P35462 | 3/20 | 0.60 |
| ▸ | HTR1D | P28221 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HTR1B | P28222 | 1/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.60 |
| ▸ | HTR2B | P41595 | 1/20 | 0.60 |
| ▸ | HTR5A | P47898 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8315435 | 0.92 | HTR1A (0.71) | HTR1AHTR7DRD2DRD3HTR1D | |
| SCHEMBL9183738 | 0.86 | DRD2 (0.58) | HTR1AHTR7DRD2DRD3HTR1D | |
| Hydrochloric Acid SCHEMBL6961243 | 0.85 | DRD2 (0.57) | HTR1AHTR7DRD2DRD3HTR1D | |
| SCHEMBL8892193 | 0.82 | HTR1A (1.00) | HTR1AHTR7DRD2DRD3HTR1D | |
| SCHEMBL9190906 | 0.82 | HTR1A (0.70) | HTR1AHTR7DRD2DRD3HTR1D | |
| SCHEMBL8891564 | 0.81 | DRD2 (0.75) | HTR1AHTR7DRD2DRD3HTR1D | |
| SCHEMBL9759195 | 0.79 | DRD2 (0.52) | DRD2DRD3 | |
| SCHEMBL9186160 | 0.78 | CHRM3 (0.67) | HTR1AHTR7DRD2DRD3HTR1D | |
| SCHEMBL9189284 | 0.77 | HTR1D (0.46) | HTR1AHTR7DRD2DRD3HTR1D | |
| SCHEMBL6542199 | 0.76 | HTR1A (0.72) | HTR1AHTR7DRD2DRD3HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389687-A | Selective antagonists of serotonin | ELI LILLY AND COMPANY (US) | 1995-02-14 | — | — | US | disclosed |