Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19105368 | 0.90 | TSHR (0.38) | TSHRSLC1A2MEN1KMT2AMME | |
| SCHEMBL11881750 | 0.87 | ZDHHC7 (0.39) | TSHRMEN1KMT2AMMECA1 | |
| SCHEMBL9432674 | 0.83 | TSHR (0.42) | TSHRSLC1A2MEN1KMT2ATP53 | |
| SCHEMBL855064 | 0.83 | MEN1 (0.44) | TSHRSLC1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15455352 | 0.81 | TSHR (0.41) | TSHRSLC1A2MEN1KMT2ATP53 | |
| SCHEMBL4441158 | 0.79 | SLC1A2 (0.47) | TSHRSLC1A2MEN1KMT2ATP53 | |
| SCHEMBL4955166 | 0.76 | TSHR (0.41) | TSHRSLC1A2MEN1KMT2AMME | |
| SCHEMBL9190854 | 0.76 | TSHR (0.37) | TSHRSLC1A2TP53NLRP3 | |
| SCHEMBL4771674 | 0.75 | CA1 (0.45) | TSHRMMECA1CA2SMN1; SMN2 | |
| SCHEMBL6922837 | 0.75 | ZDHHC7 (0.47) | TSHRMMECA1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530696-B1 | Process for the preparation of pentane 1,5-diamines | BASF AG (DE) | 1995-08-09 | — | — | EP | disclosed |
| US-5344983-A | Selective preparation of linear pentane-1,5-diamines in increased yields | BASF AKTIENGESELLSCHAFT (DE) | 1994-09-06 | — | — | US | disclosed |
| EP-0530696-A2 | Process for the preparation of pentane 1,5-diamines | BASF Aktiengesellschaft (DE) | 1993-03-10 | — | — | EP | disclosed |
| US-4614807-A | ANTIFERTILITY AGENTS | ELI LILLY AND COMPANY (US) | 1986-09-30 | — | — | US | disclosed |