Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.69 |
| ▸ | DRD4 | P21917 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982536 | 0.82 | DRD3 (1.00) | DRD3DRD2 | |
| SCHEMBL6984893 | 0.77 | DRD3 (1.00) | DRD3DRD4DRD2 | |
| SCHEMBL4006809 | 0.70 | DRD4 (0.76) | DRD3DRD4DRD2 | |
| SCHEMBL8744497 | 0.70 | SLC6A4 (0.61) | DRD3DRD4DRD2HTR1AHTR2A | |
| SCHEMBL8744499 | 0.69 | DRD4 (0.58) | DRD3DRD4DRD2HTR1AHTR2A | |
| SCHEMBL8744506 | 0.69 | SLC6A4 (0.59) | DRD3DRD4DRD2HTR1AHTR2A | |
| SCHEMBL14761329 | 0.69 | HTR1A (0.67) | DRD3DRD4DRD2HTR1AHTR2A | |
| SCHEMBL5658247 | 0.68 | HTR1A (0.53) | DRD4DRD2HTR1AHTR2AADRA1A | |
| SCHEMBL6986277 | 0.67 | DRD3 (1.00) | DRD3DRD4DRD2 | |
| SCHEMBL5658252 | 0.67 | ALDH1A1 (0.59) | DRD3DRD4DRD2HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395835-A | Antipsychotic agents | WARNER-LAMBERT COMPANY (US) | 1995-03-07 | — | — | US | disclosed |